Strategies Employing Transition Metal Complexes To Modulate Amyloid-β Aggregation
نویسندگان
چکیده
منابع مشابه
Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease.
Alzheimer's disease is the most common form of age-related neurodegenerative dementia. The disease is characterised by the presence of plaques in the cerebral cortex. The major constituent of these plaques is aggregated amyloid-β peptide. This review focuses on the molecular aspects of metal complexes designed to bind to amyloid-β. The development of radioactive metal-based complexes of copper ...
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ژورنال
عنوان ژورنال: Inorganic Chemistry
سال: 2018
ISSN: 0020-1669,1520-510X
DOI: 10.1021/acs.inorgchem.8b02813